From 37e385fe94e55e54f9b9e2215d190aad56818b4b Mon Sep 17 00:00:00 2001 From: "W. Trevor King" Date: Fri, 21 Jun 2013 14:45:09 -0400 Subject: [PATCH] sawsim/discussion.tex: Flesh out testing procedure Prof. Cruz thought the existing lead in wasn't clear. --- src/sawsim/discussion.tex | 11 ++++++++++- 1 file changed, 10 insertions(+), 1 deletion(-) diff --git a/src/sawsim/discussion.tex b/src/sawsim/discussion.tex index ec9d006..0f0456e 100644 --- a/src/sawsim/discussion.tex +++ b/src/sawsim/discussion.tex @@ -605,7 +605,16 @@ becomes difficult to convince others (or yourself) that it's actually working correctly. In order to test \sawsim, I've developed a test suite (distributed with \sawsim) that compares simulated unfolding force histograms with analytical histograms for a number of situations -where solving for the analytical histogram is possible. +where solving for the analytical histogram is possible. In the +following subsection, I'll work out the theoretical unfolding force +distribution for a number of tractable cases. The sawsim test suite +generates simulated unfolding curves for these tractable cases +(e.g. single domain Bell model unfolding with a constant loading +rate), and compares the simulated unfolding force histograms with the +expected theoretical distribution. The simulated histograms match the +theoretical distributions for each combination of models regardless of +the parameters you feed into the models, so we can be confident that +\sawsim\ correctly implements at those models. The instantaneous likelyhood of a protein unfolding is given by $\deriv{F}{N_u}$, and the unfolding histogram is merely this function -- 2.26.2