\chapter{Introduction}
\label{sec:intro}
+Single molecule force spectroscopy (SMFS) is the study of folding and
+unfolding transitions in proteins under tension. By measuring these
+transitions, we hope to gain insight into fundamental protein
+behavior. SMFS is an attempt to bridge the gap between chemists
+studying folding and unfolding kinetics in bulk solutions and
+theorists simulating protein behavior at the amino-acid level. An
+increased understanding of protein folding would guide researchers in
+developing drugs targeting biologically significant receptors and
+enzymes. In this chapter, I describe the protein folding problem in a
+general sense (\cref{sec:folding-problem}), discuss theoretical
+frameworks for understanding protein folding
+(\cref{sec:energy-landscape}), and highlight the role of SMFS in
+extending this understanding (\cref{sec:single-molecule}).
+
\section{The Protein Folding Problem}
\label{sec:folding-problem}