There are a number of open source packages dealing with aspects of
-single-molecule force spectroscopy. Here's a list of everything I've
-heard about to date.
-
-============= =========== ======================================================
-Package License Purpose
-============= =========== ======================================================
-[[calibcant]] GPL v3+ Cantilever thermal calibration
-[fs_kit][] GPL v2+ Force spectra analysis pattern recognition
-[Hooke][] LGPL v3+ Force spectra analysis and unfolding force extraction
-[[sawsim]] GPL v3+ Monte Carlo unfolding/refolding simulation and fitting
-[refolding][] Apache v2.0 Double-pulse experiment control and analysis
-============= =========== ======================================================
+[[single-molecule force spectroscopy|force_spectroscopy]]. Here's a
+list of everything I've heard about to date.
+
+<table>
+ <thead>
+ <tr><th>Package</th><th>License</th><th>Purpose</th></tr>
+ </thead>
+ <tbody>
+ <tr><td>calibcant</td><td>GPL v3+</td>
+ <td>Cantilever thermal calibration</td></tr>
+ <tr><td>fs_kit</td><td>GPL v2+</td>
+ <td>Force spectra analysis pattern recognition</td></tr>
+ <tr><td>Hooke</td><td>LGPL v3+</td>
+ <td>Force spectra analysis and unfolding force extraction</td></tr>
+ <tr><td>sawsim</td><td>GPL v3+</td>
+ <td>Monte Carlo unfolding/refolding simulation and fitting</td></tr>
+ <tr><td>refolding</td><td>Apache v2.0</td>
+ <td>Double-pulse experiment control and analysis</td></tr>
+ </tbody>
+</table>
calibcant
=========
[fs_kit][] is a package for force spectra analysis pattern
recognition. It was developed by Michael Kuhn and Maurice Hubain at
-Daniel Müller's lab when they were at TU~Dresden
+Daniel Müller's lab when they were at TU Dresden
([paper][fs_kit_paper]). It has an [[Igor]] interface, but the bulk
of the project is in [[C++]] with a [wxWidgets][] interface. fs_kit
is versioned in CVS at `bioinformatics.org`, and you can check out
The last commit was on 2005/05/16, so it's a bit crusty. I patched
things up back in 2008 so it would compile again,
-[[!inline pages="./Open_source_force_spectroscopy/*.patch" archive=yes quick=yes]]
+[[!inline pages="./Open_source_force_spectroscopy/*.patch"
+ sort="title" archive=yes quick=yes]]
but when I emailed Michael with the patches I got this:
So, it's a bit of a fixer-upper, but it was the first open source
package in this field that I know of. I've put up a [[PDF
-version|fs_kit_tutorial]] of the tutorial Michael sent me in case
+version|fs_kit_tutorial.pdf]] of the tutorial Michael sent me in case
you're interested.
Hooke
=====
-[Hooke][] is a [[force spectroscopy]] data analysis package written in
+[Hooke][] is a force spectroscopy data analysis package written in
[[Python]]. It was initially developed by Massimo Sandal, Fabrizio
Benedetti, Marco Brucale, Alberto Gomez-Casado while at Bruno Samorì's
-lab at U~Bologna ([paper][hooke_paper]. Suprisingly, there are
+lab at U Bologna ([paper][hooke_paper]; surprisingly, there are
commits by all of the authors except Samorì himself). Hooke provides
the interface between your raw data and theory. It has a drivers for
reading most force spectroscopy file formats, and a large number of