the folding behavior.
Practically, the distinction between folding and unfolding makes
-little difference, as drug designers and doctors are not consuming
-SMFS results directly. For researchers calibrating molecular dynamics
-simulations, it doesn't matter if you compare simulated folding
-experiments with experimental folding experiments, or simulated
-unfolding experiments with experimental unfolding experiments. The
-important thing is to compare your simulation against \emph{some}
-experimental benchmarks. If your molecular dynamics simulation
-successfully predicts a protein's unfolding behavior, it makes me more
-confident that it will correctly predict the protein's native folding
-behavior.
+little difference, because drug designers and doctors are not
+consuming SMFS results directly. For researchers calibrating
+molecular dynamics simulations, it doesn't matter if you compare
+simulated folding experiments with experimental folding experiments,
+or simulated unfolding experiments with experimental unfolding
+experiments. The important thing is to compare your simulation
+against \emph{some} experimental benchmarks. If your molecular
+dynamics simulation successfully predicts a protein's unfolding
+behavior, it makes me more confident that it will correctly predict
+the protein's native folding behavior.
\section{Thesis outline}