2 \label{sec:cantilever:simulations}
4 As discussed in \cref{sec:sawsim:cantilever}, we can model the I27
5 multimers as an array of Bell-model unfolders in series with a
6 cantilever. Any unfolded domains also contribute to the tension
7 according to the WLC\index{WLC} tension formula. Completing 1000
8 simulated pulls for each cantilever/pulling-speed/multimer-number
9 combination with our \sawsim\ Monte Carlo simulator yielded the
11 (\cref{fig:cant:sim:v-dep,fig:cant:sim:load-dep,fig:cant:sim:i-dep}).
14 \asyinclude{figures/cantilever-sim/v-dep}
15 \caption{Unfolding force velocity dependence for different
16 cantilevers.\label{fig:cant:sim:v-dep}}
20 \asyinclude{figures/cantilever-sim/loading-rate}
21 \caption{Unfolding force loading rate dependence simulations for
22 different cantilevers.\label{fig:cant:sim:load-dep}}
26 \asyinclude{figures/cantilever-sim/i-dep}
27 \caption{Unfolding force peak index dependence simulations for
28 different cantilevers.\label{fig:cant:sim:i-dep}}
33 %size(6cm,4cm,IgnoreAspect);
34 %scale(Linear, Linear);
38 %graphFile("cantilever/stiffness_force-127_8", xscale, yscale, phard, m30, t=units("127","pN/nm"), dots=true);
39 %graphFile("cantilever/stiffness_force-27_8", xscale, yscale, phard, m8, t=units("27","pN/nm"), dots=true);
44 %label(sLabel("Sawtooth curves ("+units("v = 1","$\mu$m/s")+", 8 domains)"), point(N),N);
45 %xaxis(sLabel("Distance (nm)"),BottomTop,LeftTicks);
46 %yaxis(sLabel("Tension (pN)"),Left,RightTicks);
48 %picture q=secondaryY(new void(picture pic) {
49 % scale(pic,Linear,Linear);
50 % graphFile(pic, "cantilever/stiffness_stiffness-127_8", xscale, 1e3, pmed, m30, dots=true);
51 % graphFile(pic, "cantilever/stiffness_stiffness-27_8", xscale, 1e3, pmed, m8, dots=true);
52 % ylimits(pic, 0, 130);
53 % yaxis(pic, sLabel("Stiffness (pN/nm)"),Right, LeftTicks);
57 %add(legend(),point(E)+(24pt,0),20E,UnFill);